Welcome
Research in our laboratory is focused upon how the structure of hemoprotein cytochrome P450 (CYP) dependent monooxygenases controls their function in normal metabolic processes, removal of environmental toxins, and therapeutic drug metabolism. Our group has more than three decades of experience studying these enzymes.
Using a variety of biochemical, biophysical, and structural biology techniques, our recent work has focused upon the interaction of CYP2B enzymes and monoterpenoids, characterization of novel CYP2B enzymes from the desert woodrat, and the role of protein-protein interactions in CYP3A4 allostery.
Events
The 22nd International Symposium on Microsomes and Drug Oxidations and 33rd JSSX Meeting; Kanazawa, Japan; October 1 - 5, 2018; Meeting Website
Experimental Biology 2019; Orlando, FL, USA; April 6 - 9, 2019
21st International Conference on Cytochromes P450; Brisbane, Australia; June 23-27, 2019; Meeting Website